Circhectd1

Author: inlh

August undefined, 2024

WebcircHECTD1 or PBX3 was expounded by dual-luciferase reporter, RNA immunoprecipitation (RIP) and RNA pull down assays. Results: We uncovered that circHECTD1 was ectopically up-regulated in GC tissues and cells. CircHECTD1 deciency sensitized DB-treatment in DB-evoked AGS and HGC-27 cells. In vivo assay, circHECTD1 silencing led to the tumor ...

circHECTD1 attenuates apoptosis of alveolar epithelial cells in …

WebFeb 9, 2024 · Knockdown of circHECTD1 inhibited proliferation and invasion in vitro, and also reduced the growth of tumor and prolonged the prognosis in vivo. Knockdown of circHECTD1 significantly elevated the miR-296-3p expression in LN229 and T98G cells. Luciferase reports and RNA immunoprecipitation data indicated that miR-296-3p was a … WebMay 27, 2024 · In GC, circHECTD1 promotes ubiquitin carboxyl-terminal hydrolase 5 expression by targeting miR-1256. In the present study, we found complementary sequences between circHECTD1 and miR-485-5p through Starbase 2.0 analysis, and subsequently, it was proved by RIP and luciferase reporter assays that circHECTD1 … dylan coleman reference

circHECTD1 promotes the proliferation of smooth muscle …

WebMay 17, 2024 · CircHECTD1 Lentivirus, miR-320-5p mimic, and SLC2A1 Lentivirus were transduced into cancer cells independently or together. circHECTD1, miR-320-5p, and SLC2A1 level were detected by qRT-PCR. WebApr 1, 2024 · The circHECTD1 expression level was found to be an independent prognostic factor for GC patients. circHECTD1 knockdown inhibited GC cell glutaminolysis, proliferation, migration, and invasion ... WebFeb 9, 2024 · Knockdown of circHECTD1 inhibited proliferation and invasion in vitro, and also reduced the growth of tumor and prolonged the prognosis in vivo. Knockdown of … crystals for winning court cases

circHECTD1 facilitates glutaminolysis to promote gastric …

circHECTD1 attenuates apoptosis of alveolar epithelial cells in …

WebAug 2, 2024 · Our results revealed that circHECTD1 is a glutaminolysis-associated circRNA that promotes GC progression. The circHECTD1/miR-1256/USP5 axis could thus be used as a therapeutic target for GC. WebMay 17, 2024 · Methods. Quantitative real-time polymerase chain reaction (qRT-PCR) was employed to examine the expression profiles of circHECTD1, microRNA (miR)-137, and … crystals for women\u0027s healthWebSep 1, 2024 · The relationships between circHECTD1, miRNAs, and target genes were assessed by RNA pull-down, luciferase reporter gene, and RNA-FISH assays. circHECTD1 was downregulated in LPS-induced human and mouse AECs (HBE and MLE-12). The knockdown of circHECTD1 increased the apoptotic rates and the expressions of miR … crystals for window cleaner

"WebAug 1, 2024 · The circHECTD1 expression level was found to be an independent prognostic factor for GC patients. circHECTD1 knockdown inhibited GC cell glutaminolysis, proliferation, migration, and invasion ... " - Circhectd1

Circhectd1

WebcircHECTD1 in IS. qRT-PCR and western blot were used to test gene and protein expressions, respectively. CCK-8 assay was used to investigate the cell viability. Moreover, cell migration and tube formation were assessed by transwell and tube formation assays. In addition, RIP and luciferase assay were performed to explore the association among ... WebNov 27, 2024 · After exposure to SiO 2, the circHECTD1 level was decreased, which was associated with an increase in HECTD1 in HPF-a cells.SiO 2-induced autophagy was reversed by either circHECTD1 overexpression or HECTD1 knockdown in HPF-a cells, with restored SiO 2-induced fibroblast activation, proliferation, and migration via downstream …

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WebNov 27, 2024 · The downregulation of circHECTD1 was associated with an upregulation of HECTD1, which mediates autophagy in fibroblasts exposed to silica, thereby regulating the activation, proliferation, and ... http://www.globalauthorid.com/WebPortal/AuthorView?wd=GAID10949136&rc=212N32

WebCircHECTD1 was verified to bind with KHDRBS3 and increase the EZH2 mRNA stability. Importantly, the influence of circHECTD1 on the proliferation and migration of VSMCs … WebMar 14, 2024 · circHECTD1 is involved in SiO 2-induced HECTD1 downregulation. a In the SiO 2-induced EndMT, circHECTD1 may regulate the expression of its host gene, …

WebDec 21, 2024 · Circular RNA circHECTD1 facilitates glioma progression by regulating the miR-296-3p/SLC10A7 axis. The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1. CircHECTD1 up-regulates mucin 1 expression to accelerate hepatocellular carcinoma development by targeting microRNA-485-5p via a competing … WebSep 1, 2024 · The knockdown of circHECTD1 increased the apoptotic rates and the expressions of miR-136 and miR-320a, while its overexpression caused opposite effects in LPS-induced HBE and MLE-12 cells. Mechanistically, circHECTD1 bound to miR-320a and miR-136. miR-320a targeted PIK3CA and mediated the effect of circHECTD1 on …

WebMar 24, 2024 · Abstract. Purpose. The objective of this paper is to explore the role of circHECTD1 in vascular smooth muscle cells (VSMCs) and atherosclerosis (AS). …

WebApr 19, 2024 · Circular RNAs (circRNAs) play important roles in many lung diseases. This study aimed to investigate the role of circHECTD1 in acute lung injury (ALI). The mouse … dylan coleman scotuing reportWebMay 17, 2024 · CircHECTD1 knockdown suppressed GC tumor growth in vivo. Nude mice were injected with lentivirus-mediated AGS cells with sh-circHECTD1 or sh-NC treatment. a QRT-PCR analysis for the expression of ... dylan coleman newsWebSep 1, 2024 · Abstract. Circular RNAs (circRNAs) play important roles in many lung diseases. This study aimed to investigate the role of circHECTD1 in acute lung injury … crystals for wisdom and knowledgeWebMar 6, 2024 · Circular RNA HECTD1 (circHECTD1), for the first time, has been found to have roles in HS physiology. We determined the relative circHECTD1 levels in HS fibrous cells and tissues by RT-qPCR. Afterward, the effect of circHECTD1 knockdown on the proliferation, migration, invasion, fibrosis, and Transforming Growth Factor-beta/small … dylan cole neosho moWebMar 24, 2024 · circHECTD1 Promotes the Proliferation and Migration of Human Brain Vascular Smooth Muscle Cells via Interacting with KHDRBS3 to Stabilize EZH2 mRNA … dylan collins deathWebMar 24, 2024 · Purpose: The objective of this paper is to explore the role of circHECTD1 in vascular smooth muscle cells (VSMCs) and atherosclerosis (AS). Methods: VSMCs were … dylan collisWebApr 19, 2024 · The knockdown of circHECTD1 increased the apoptotic rates and the expressions of miR-136 and miR-320a, while its overexpression caused opposite effects in LPS-induced HBE and MLE-12 cells. Mechanistically, circHECTD1 bound to miR-320a and miR-136. miR-320a targeted PIK3CA and mediated the effect of circHECTD1 on … crystals for window cleaning